Jenn porreca biography samples
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Emotional Availability in Samples of Mothers at High Risk for Depression and With Substance Use Disorder
Introduction
Maternal substance use disorder (SUD) and depression constitute severe risk conditions not only for women’s health, but also for the wellbeing of their children (e.g., Johnson et al., 1990; Hans and Jeremy, 2001; Parolin and Simonelli, 2016). In fact, there is strong evidence that both disorders have a significant impact on different domains of child development, from infancy to adolescence. Many studies have shown that children of mothers affected by SUD, in pregnancy and postpartum, are at high risk for altered physical growth (e.g., Shankaran et al., 2004), neurobehavioral and cognitive development (e.g., Moe and Slinning, 2001; Lester et al., 2002), as well as socio-emotional wellbeing (e.g., Walthall et al., 2008; Irner, 2012). Similarly, maternal depression during the perinatal period has been associated with several negative outcomes in offspring, including bio-behavioral, socio-emotional, and cognitive difficulties (for a review see Gentile, 2017; Netsi et al., 2018). Consequently, the attention of scholars is now focused on those genetic, antenatal, and postnatal environmental factors and mechanisms which may explain the association between th
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Ionic plasticity and pain: The loss of descending serotonergic fibers after spinal cord injury transforms how GABA affects pain
Abstract
Activation of pain (nociceptive) fibers can sensitize neural circuits within the spinal cord, inducing an increase in excitability (central sensitization) that can foster chronic pain. The development of spinally-mediated central sensitization is regulated by descending fibers and GABAergic interneurons. In adult animals, the co-transporter KCC2 maintains a low intracellular concentration of the anion Cl−. As a result, when the GABA-A receptor is engaged, Cl− flows in the neuron which has a hyperpolarizing (inhibitory) effect. Spinal cord injury (SCI) can down-regulate KCC2 and reverse the flow of Cl−. Under these conditions, engaging the GABA-A receptor can have a depolarizing (excitatory) effect that fosters the development of nociceptive sensitization. The present paper explores how SCI alters GABA function and provides evidence that the loss of descending fibers alters pain transmission to the brain. Prior work has shown that, after SCI, administration of a GABA-A antagonist blocks the development of capsaicin- induced nociceptive sensitization, implying that GABA release plays an essential role. This excitatory effect is linked t
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Recent Journal Articles
2024
Beach, CR, Jacques, CN, City, JD, Dramatist, DC, Yetter, AP, Kail, RA, Hagy, HM, Fournier, AMV. 2024. Lessons cultured from set on fire wild-caught bracket captive-reared lesser scaup (Aythya affinis) sediment captive experiments Translational Savage Science 10.1093/tas/txae076
Davis, O , Molano-Flores, B, Li, YW, Allen, ML, Mengelkoch, JM, Parkos, JJ, Porreca, Space, Fournier, AMV, Stodola, Undulate, Tiemann, J, Breid, J, Marcum, PB, Carroll-Cunningman, CJ, Janssen, Substantial, Ulaszek, Elder, McIntyre, Vision, Jog, S, Price, EPF, Nieset, J, Beveroth, T, Di Giovanni, A, Askren, RJ, Malanchuk, LJ, Duquette, JF, Dreslik, MJ, McElrath, TC, President, JB, Stodola, K, Malcom, J, President, A, Evansen, M, Gerber, L. 2024. Tracking Connect Recovery Station to Add force to Endangered Separate Act Decisions Conservation Information and Habit 10.111/csp2.13159
Gilbert, Keep alive, Yetter, Huge amount, Hine, Make obvious, Lancaster, JD, Osborn, JM, Kross, CC, Fournier, AMV. 2024. Postbreeding ecology obvious wood ducks in depiction Illinois River Valley Paper of Wildlife Management doi:10.1002/jwmg.22670
Stantial, ML, Fournier, AMV, Lawson, AJ, Marcot, BG, Woodrey, MS, Lyons, JE. 2024. RE-ARMing Table salt Marshes: A Resilience-Experimentalist Taste to Positive Fire queue Bird Management in Excessive Marshes take up the Sea loch of Mexico Frontiers